CYP2T1P

Across TCGA pan-cancer cohorts, CYP2T1P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CYP2T1P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CYP2T1P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CYP2T1P expression acts as an unfavorable survival marker, although some lineages such as UVM and CESC show a favorable association.

UVM, CESC, and KIRC are the cancer types where CYP2T1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	II,III,IV	0.737	0.420	<.001	80	view →
CESC	OS	Quartile	II,III,IV	0.930	0.706	.010	48	view →
KIRC	DFS	Tertile	II,III,IV	0.638	0.287	.002	47	view →
UCEC	OS	Median	All	0.840	0.903	.011	44	view →
HNSC	DFS	Tertile	IV	0.493	0.296	.004	43	view →
THCA	DFS	Quartile	All	0.932	0.592	.004	36	view →
LIHC	OS	Tertile	II,III,IV	0.500	0.744	.009	30	view →
MESO	OS	Median	IV	0.811	0.349	.003	24	view →
SKCM	OS	Tertile	All	0.830	0.926	.002	21	view →
ACC	DFS	Tertile	All	0.848	0.517	.011	19	view →
OV	DFS	Quartile	II,III,IV	0.128	0.231	.019	18	view →
PAAD	DFS	Quartile	II,III,IV	0.567	0.311	.012	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CYP2T1P–UVM (DFS)

Open the UVM breakdown →