CYP2C59P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYP2C59P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,727 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYP2C59P-associated GO terms across cancer lineages are Cellular modified amino acid metabolic process, Neutral lipid metabolic process, and Nucleoside phosphate biosynthetic process. Each is linked with CYP2C59P in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP2C59P-to-partner and partner-to-CYP2C59P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular modified amino acid metabolic process grouped by CYP2C59P-low versus CYP2C59P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2C59P→partner) and Y-score (partner→CYP2C59P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADCellular modified amino acid metabolic process →+0.059+0.108<.001<.00134
STADNeutral lipid metabolic process →+0.061+0.115<.001<.00134
STADNucleoside phosphate biosynthetic process →+0.092+0.112<.001<.00134
STADGlycerolipid biosynthetic process →+0.085+0.125<.001<.00134
STADRegulation of lipid biosynthetic process →+0.065+0.112<.001<.00134
UCECAerobic respiration →+0.115+0.031<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,727 associations by consensus.

Cellular modified amino acid metabolic process by CYP2C59P expression — STAD

Box plot of Cellular modified amino acid metabolic process in CYP2C59P-low vs CYP2C59P-high samples in STAD.

Explore this box plot interactively →

Exploration