Across TCGA cell cohorts, CYP2A13 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP2A13-associated genes across cancer lineages are OR7E24, KRTAP5-4, and USP17L20. Each is linked with CYP2A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYP2A13-to-partner and partner-to-CYP2A13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP2A13→partner) and Y-score (partner→CYP2A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR7E24 →	+0.022	+4.369	<.001	.008	3	1
SOFT_TISSUE	KRTAP5-4 →	+0.024	+4.369	<.001	.008	3	1
SOFT_TISSUE	USP17L20 →	+0.029	+4.222	<.001	.007	3	1
LARGE_INTESTINE	TPD52L3 →	+0.056	+4.684	<.001	.002	3	1
LARGE_INTESTINE	GPR171 →	+0.019	+4.273	<.001	.006	3	1
LARGE_INTESTINE	ADIG →	+0.041	+5.562	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CYP2A13 survival (RNA) · tumor vs normal (RNA) · all CYP2A13 data types