CYP26B1

Across TCGA cell cohorts, CYP26B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,257 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYP26B1-associated GO terms across cancer lineages are Diterpenoid catabolic process, Retinoic acid catabolic process, and Regulation of skeletal muscle fiber differentiation. Each is linked with CYP26B1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CYP26B1-to-partner and partner-to-CYP26B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Diterpenoid catabolic process grouped by CYP26B1-low versus CYP26B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP26B1→partner) and Y-score (partner→CYP26B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Diterpenoid catabolic process →	+1.933	+3.499	<.001	<.001	3	16
BONE	Retinoic acid catabolic process →	+1.933	+3.499	<.001	<.001	3	16
STOMACH	Regulation of skeletal muscle fiber differentiation →	+1.495	+2.967	<.001	<.001	3	15
STOMACH	Positive regulation of skeletal muscle fiber differentiation →	+1.495	+2.967	<.001	<.001	3	15
STOMACH	Tongue morphogenesis →	-0.245	-1.815	<.001	<.001	3	15
STOMACH	Negative regulation of retinoic acid receptor signaling pathway →	-0.226	-2.128	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,257 associations by consensus.

Diterpenoid catabolic process by CYP26B1 expression — BONE

Explore this box plot interactively →