CYP26A1

Across TCGA patient cohorts, CYP26A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,484 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP26A1-associated proteins across cancer lineages are ENPP1, THBS1, and PDLIM4. Each is linked with CYP26A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYP26A1-to-partner and partner-to-CYP26A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP26A1 versus ENPP1 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP26A1→partner) and Y-score (partner→CYP26A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ENPP1 →	+0.724	+0.419	<.001	<.001	3	6
BRCA	THBS1 →	+1.160	+0.625	<.001	<.001	3	5
OV	PDLIM4 →	+0.515	+0.470	<.001	<.001	3	5
PDAC	SMOC2 →	+1.077	+1.036	<.001	<.001	3	5
GBM	FHL2 →	+0.510	+0.230	<.001	<.001	3	5
BRCA	MSRB3 →	+0.615	+0.496	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,484 associations by consensus.

CYP26A1 vs ENPP1 — OV

Explore this scatter interactively →