CYP26A1

Across TCGA cell cohorts, CYP26A1 RNA expression is significantly associated with the RNA expression of many other genes, with 4,858 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYP26A1-associated genes across cancer lineages are PHC2, EVI2A, and LRFN1. Each is linked with CYP26A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP26A1-to-partner and partner-to-CYP26A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP26A1 versus PHC2 in LUNG_NSCLC_LUSC, with a Pearson correlation of -0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP26A1→partner) and Y-score (partner→CYP26A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PHC2 →	-1.574	-2.116	<.001	<.001	3	4
CNS	EVI2A →	-1.870	-0.543	<.001	.003	3	4
SOFT_TISSUE	LRFN1 →	+1.485	+2.381	<.001	<.001	2	5
SOFT_TISSUE	ANTXR2 →	-2.378	-1.458	<.001	<.001	3	4
LUNG_NSCLC_LUSC	HAP1 →	+1.694	+2.037	.001	.001	3	4
SOFT_TISSUE	GPLD1 →	+0.668	+1.901	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,858 associations by consensus.

CYP26A1 vs PHC2 — LUNG_NSCLC_LUSC

Explore this scatter interactively →