CYP1B1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYP1B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,790 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP1B1-associated proteins across cancer lineages are PCOLCE, RCN3, and SERPINF1. Each is linked with CYP1B1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CYP1B1-to-partner and partner-to-CYP1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP1B1 versus PCOLCE in GBM, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP1B1→partner) and Y-score (partner→CYP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPCOLCE →+0.805+1.323<.001<.001310
GBMRCN3 →+0.916+1.551<.001<.001310
COADSERPINF1 →+0.828+1.621<.001<.001310
OVRARRES2 →+0.913+1.856<.001<.00139
COADRASSF2 →+0.465+1.451<.001<.00139
OVMXRA5 →+0.932+1.789<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,790 associations by consensus.

CYP1B1 vs PCOLCE — GBM

Per-sample scatter of CYP1B1 vs PCOLCE in GBM (Pearson r = 0.59).

Explore this scatter interactively →

Exploration