CYP1B1

Across TCGA patient cohorts, CYP1B1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,025 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYP1B1-associated genes across cancer lineages are CXCL12, FAM20A, and CYP1B1-AS1. Each is linked with CYP1B1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYP1B1-to-partner and partner-to-CYP1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP1B1 versus CXCL12 in OV, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP1B1→partner) and Y-score (partner→CYP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CXCL12 →	+1.919	+1.163	<.001	<.001	3	8
OV	FAM20A →	+1.243	+0.665	.003	.004	3	8
HNSC	CYP1B1-AS1 →	+0.822	+0.854	<.001	<.001	3	8
OV	CLMP →	+1.771	+1.182	<.001	<.001	3	7
COAD	PLEK →	+1.395	+1.839	<.001	<.001	3	7
OV	PTGIS →	+1.985	+1.176	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,025 associations by consensus.

CYP1B1 vs CXCL12 — OV

Explore this scatter interactively →