CYP1B1

Across TCGA cell cohorts, CYP1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,888 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CYP1B1-associated GO terms across cancer lineages are Omega-hydroxylase P450 pathway, Retina vasculature development in camera-type eye, and Epoxygenase P450 pathway. Each is linked with CYP1B1 in more than 17 cancer types. Because this analysis shows association rather than direction, both CYP1B1-to-partner and partner-to-CYP1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Omega-hydroxylase P450 pathway grouped by CYP1B1-low versus CYP1B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP1B1→partner) and Y-score (partner→CYP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Omega-hydroxylase P450 pathway →	+1.929	+3.985	<.001	<.001	3	18
BLOOD_Lymphoma	Retina vasculature development in camera-type eye →	+0.770	+2.966	.002	<.001	3	12
BONE	Epoxygenase P450 pathway →	+2.270	+4.218	<.001	<.001	3	11
LIVER	Collagen fibril organization →	+0.282	+3.374	.006	.006	2	11
BLOOD_Lymphoma	Response to acid chemical →	+0.035	+1.937	.003	.001	3	9
BLOOD_Lymphoma	Proteasomal ubiquitin-independent protein catabolic process →	+0.086	+2.677	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,888 associations by consensus.

Omega-hydroxylase P450 pathway by CYP1B1 expression — BONE

Explore this box plot interactively →