CYP11B2

Across TCGA patient cohorts, CYP11B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,074 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYP11B2-associated GO terms across cancer lineages are Aerobic respiration, Oxidative phosphorylation, and Steroid biosynthetic process. Each is linked with CYP11B2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CYP11B2-to-partner and partner-to-CYP11B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by CYP11B2-low versus CYP11B2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP11B2→partner) and Y-score (partner→CYP11B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Aerobic respiration →	+0.099	+0.058	<.001	<.001	3	10
STAD	Oxidative phosphorylation →	+0.103	+0.054	<.001	<.001	3	10
STAD	Steroid biosynthetic process →	+0.060	+0.053	<.001	<.001	3	9
STAD	Proton motive force-driven ATP synthesis →	+0.110	+0.052	<.001	<.001	3	9
STAD	Glycolipid transport →	+0.068	+0.055	<.001	<.001	3	8
STAD	Electron transport chain →	+0.092	+0.062	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,074 associations by consensus.

Aerobic respiration by CYP11B2 expression — STAD

Explore this box plot interactively →