CYP11A1

Across TCGA patient cohorts, CYP11A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,047 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CYP11A1-associated proteins across cancer lineages are STRBP, SYNPO2_S363, and CAVIN3. Each is linked with CYP11A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYP11A1-to-partner and partner-to-CYP11A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYP11A1 versus STRBP in LSCC, with a Pearson correlation of -0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYP11A1→partner) and Y-score (partner→CYP11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STRBP →	-0.540	-0.504	<.001	<.001	3	5
BRCA	SYNPO2_S363 →	+0.954	+0.447	.004	<.001	3	5
PDAC	CAVIN3 →	+0.614	+0.343	<.001	<.001	3	5
BRCA	SNTB2 →	+0.392	+0.445	<.001	.004	3	4
PDAC	SORBS3_S530 →	+0.582	+0.347	<.001	<.001	3	4
COAD	SPON1 →	+0.711	+0.176	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,047 associations by consensus.

CYP11A1 vs STRBP — LSCC

Explore this scatter interactively →