CYMP-AS1

Across TCGA pan-cancer cohorts, CYMP-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CYMP-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CYMP-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYMP-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and READ show a favorable association.

KIRP, ACC, and STAD are the cancer types where CYMP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	III,IV	0.111	0.697	<.001	87	view →
ACC	OS	Tertile	All	0.153	0.725	<.001	78	view →
STAD	OS	Tertile	II,III,IV	0.434	0.654	.002	60	view →
SKCM	OS	Tertile	II,III,IV	0.656	0.846	.008	33	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	27	view →
LIHC	OS	Tertile	All	0.178	0.517	.005	27	view →
MESO	DFS	Tertile	IV	0.079	0.414	.004	21	view →
UCEC	DFS	Tertile	All	0.536	0.659	.020	18	view →
LUAD	OS	Quartile	All	0.928	0.809	.007	14	view →
READ	DFS	Tertile	II,III,IV	0.774	0.430	.036	9	view →
TGCT	DFS	Median	All	0.560	0.773	.035	8	view →
OV	OS	Median	All	0.360	0.303	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CYMP-AS1–KIRP (OS)

Open the KIRP breakdown →