CYMP-AS1

Across TCGA pan-cancer cohorts, CYMP-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CYMP-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CYMP-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CYMP-AS1 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.

BRCA, STAD, and LUSC are the cancer types where CYMP-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYMP-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.024	<.001	6	view →
STAD	All	All	+0.214	.010	4	view →
LUSC	Male	II,III,IV	−0.048	.012	3	view →
PAAD	All	All	+0.867	.039	2	view →
HNSC	All	III,IV	−0.022	.045	1	view →
COAD	All	All	+0.018	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CYMP-AS1–BRCA

Open the BRCA breakdown →