CYLD

Across TCGA patient cohorts, CYLD RNA expression is significantly associated with the protein abundance of many other proteins, with 17,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYLD-associated proteins across cancer lineages are ANKRD44, UBA7, and PLCB2. Each is linked with CYLD in more than 7 cancer types. Because this analysis shows association rather than direction, both CYLD-to-partner and partner-to-CYLD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYLD versus ANKRD44 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYLD→partner) and Y-score (partner→CYLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.368	+0.594	<.001	<.001	3	8
GBM	UBA7 →	+0.485	+0.509	<.001	<.001	3	7
GBM	PLCB2 →	+0.633	+0.609	<.001	<.001	3	7
COAD	ARHGAP15 →	+0.573	+0.578	.001	<.001	3	7
GBM	ARHGAP25 →	+0.530	+0.376	<.001	.002	3	7
OV	TFB2M →	-0.507	-0.573	.002	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,088 associations by consensus.

CYLD vs ANKRD44 — OV

Explore this scatter interactively →