CYLC2

Across TCGA pan-cancer cohorts, CYLC2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CYLC2’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CYLC2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CYLC2 is over-expressed in tumor.

UCEC and KIRP are the cancer types where CYLC2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYLC2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.065	.049	2	view →
KIRP	All	All	+0.004	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

CYLC2–UCEC

Open the UCEC breakdown →