CYGB

Across TCGA patient cohorts, CYGB mutation is significantly associated with the RNA expression of many other genes, with 438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYGB-associated genes across cancer lineages are LINC01400, MIR4452, and RNU6-1064P. Each is linked with CYGB in more than 1 cancer types. Because this analysis shows association rather than direction, both CYGB-to-partner and partner-to-CYGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01400 grouped by CYGB-low versus CYGB-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYGB→partner) and Y-score (partner→CYGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC01400 →	+0.060	+4.990	<.001	.009	3	2
LUAD	MIR4452 →	+0.752	+5.554	<.001	.004	3	2
UCEC	RNU6-1064P →	+0.725	+1.931	<.001	.009	3	2
UCEC	RNU4-58P →	+0.221	+2.674	.001	.006	3	2
UCEC	WASHC3P1 →	+0.182	+2.579	.003	.001	3	2
UCEC	MAGI2-AS2 →	+0.112	+3.335	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 438 associations by consensus.

LINC01400 by CYGB expression — LUAD

Explore this box plot interactively →