CYFIP2

Across TCGA patient cohorts, CYFIP2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,161 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYFIP2-associated genes across cancer lineages are PIM2, TBC1D10C, and PRKCB. Each is linked with CYFIP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CYFIP2-to-partner and partner-to-CYFIP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYFIP2 versus PIM2 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYFIP2→partner) and Y-score (partner→CYFIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PIM2 →	+1.448	+0.730	<.001	<.001	3	7
HNSC	TBC1D10C →	+0.787	+0.446	<.001	<.001	3	7
GBM	PRKCB →	+1.119	+0.525	<.001	<.001	3	7
CCRCC	CD27 →	+0.945	+0.230	<.001	.001	3	6
HNSC	THEMIS →	+1.020	+0.482	<.001	<.001	3	6
HNSC	SELL →	+1.363	+0.548	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,161 associations by consensus.

CYFIP2 vs PIM2 — HNSC

Explore this scatter interactively →