CYCTP

Across TCGA patient cohorts, CYCTP mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CYCTP-associated genes across cancer lineages are RNU6-792P, IL9, and RN7SL51P. Each is linked with CYCTP in more than 1 cancer types. Because this analysis shows association rather than direction, both CYCTP-to-partner and partner-to-CYCTP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-792P grouped by CYCTP-low versus CYCTP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCTP→partner) and Y-score (partner→CYCTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-792P →	+0.330	+4.979	.002	.009	3	1
SKCM	IL9 →	+0.229	+5.037	<.001	.009	3	1
SKCM	RN7SL51P →	+0.145	+5.159	<.001	.007	3	1
SKCM	ADAM3B →	+0.065	+5.292	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RNU6-792P by CYCTP expression — SKCM

Explore this box plot interactively →