Across TCGA pan-cancer cohorts, CYCSP55 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CYCSP55’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CYCSP55 RNA is repressed in tumor relative to normal tissue. In most cancer types CYCSP55 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.
KIRC, UCEC, and COAD are the cancer types where CYCSP55 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYCSP55 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.