CYCSP53

Across TCGA patient cohorts, CYCSP53 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,119 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP53-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Positive regulation of cell cycle phase transition, and Positive regulation of mitotic cell cycle. Each is linked with CYCSP53 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYCSP53-to-partner and partner-to-CYCSP53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by CYCSP53-low versus CYCSP53-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP53→partner) and Y-score (partner→CYCSP53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.129	+0.114	<.001	<.001	3	6
UCEC	Positive regulation of cell cycle phase transition →	+0.119	+0.050	<.001	.002	2	6
UCEC	Positive regulation of mitotic cell cycle →	+0.127	+0.065	<.001	<.001	3	5
STAD	Oogenesis →	+0.061	+0.097	<.001	<.001	3	5
STAD	Negative regulation of DNA metabolic process →	+0.102	+0.103	<.001	<.001	3	5
STAD	Microtubule organizing center localization →	+0.127	+0.113	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,119 associations by consensus.

Ribose phosphate biosynthetic process by CYCSP53 expression — STAD

Explore this box plot interactively →