CYCSP4

Across TCGA pan-cancer cohorts, CYCSP4 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CYCSP4’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CYCSP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CYCSP4 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

BLCA, PAAD, and LIHC are the cancer types where CYCSP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYCSP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.136	.008	5	view →
PAAD	Female	All	−0.375	.004	2	view →
LIHC	All	All	+0.023	.024	2	view →
BRCA	Female	All	+0.146	.045	1	view →
LUSC	All	II,III,IV	+0.070	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CYCSP4–BLCA

Open the BLCA breakdown →