CYCSP23

Across TCGA patient cohorts, CYCSP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,432 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP23-associated GO terms across cancer lineages are Regulation of endocytosis, Negative regulation of DNA-binding transcription factor activity, and Lung alveolus development. Each is linked with CYCSP23 in more than 12 cancer types. Because this analysis shows association rather than direction, both CYCSP23-to-partner and partner-to-CYCSP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endocytosis grouped by CYCSP23-low versus CYCSP23-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP23→partner) and Y-score (partner→CYCSP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of endocytosis →	+0.052	+0.165	<.001	<.001	3	13
STAD	Negative regulation of DNA-binding transcription factor activity →	+0.053	+0.159	<.001	<.001	3	13
STAD	Lung alveolus development →	+0.049	+0.130	<.001	<.001	3	12
STAD	Rhythmic process →	+0.049	+0.166	<.001	<.001	3	12
ESCA	Regulation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.059	+0.242	<.001	<.001	3	12
STAD	Positive regulation of protein kinase activity →	+0.049	+0.142	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,432 associations by consensus.

Regulation of endocytosis by CYCSP23 expression — STAD

Explore this box plot interactively →