CYBC1

Across TCGA patient cohorts, CYBC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,473 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CYBC1-associated proteins across cancer lineages are RNF213, TNFAIP8L2, and EPB41L1_S510. Each is linked with CYBC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYBC1-to-partner and partner-to-CYBC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYBC1 versus RNF213 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYBC1→partner) and Y-score (partner→CYBC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNF213 →	+0.422	+0.358	<.001	<.001	3	6
GBM	TNFAIP8L2 →	+0.505	+0.271	.009	.004	3	5
PDAC	EPB41L1_S510 →	-0.936	-0.354	<.001	<.001	3	5
PDAC	GRB2 →	+0.263	+0.233	<.001	.005	3	4
GBM	FCER1G →	+0.653	+0.258	.002	.003	3	4
GBM	FERMT3 →	+0.479	+0.234	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,473 associations by consensus.

CYBC1 vs RNF213 — LSCC

Explore this scatter interactively →