CYBC1

Across TCGA cell cohorts, CYBC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,842 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYBC1-associated GO terms across cancer lineages are Respiratory burst after phagocytosis, Cytokinesis, and Mitotic cytokinesis. Each is linked with CYBC1 in more than 17 cancer types. Because this analysis shows association rather than direction, both CYBC1-to-partner and partner-to-CYBC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory burst after phagocytosis grouped by CYBC1-low versus CYBC1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYBC1→partner) and Y-score (partner→CYBC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Respiratory burst after phagocytosis →	+0.252	+1.009	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cytokinesis →	+0.074	+1.253	.002	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.081	+1.260	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.074	+1.253	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.061	+1.119	.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.036	+0.807	.001	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,842 associations by consensus.

Respiratory burst after phagocytosis by CYBC1 expression — LUNG_SCLC

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