CYB5R4

Across TCGA patient cohorts, CYB5R4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,691 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYB5R4-associated proteins across cancer lineages are MICAL1, COBLL1_S256, and CCDC50. Each is linked with CYB5R4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYB5R4-to-partner and partner-to-CYB5R4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5R4 versus MICAL1 in CCRCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R4→partner) and Y-score (partner→CYB5R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MICAL1 →	+0.262	+0.377	<.001	<.001	3	4
LSCC	COBLL1_S256 →	-0.898	-0.487	.002	.004	3	4
BRCA	CCDC50 →	+0.230	+0.510	.004	<.001	3	4
CCRCC	GMIP →	+0.286	+0.279	<.001	<.001	3	4
CCRCC	CD44 →	+0.489	+0.272	<.001	.002	3	3
PDAC	DOCK10_T1440 →	+0.800	+0.290	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,691 associations by consensus.

CYB5R4 vs MICAL1 — CCRCC

Explore this scatter interactively →