CYB5R4

Across TCGA patient cohorts, CYB5R4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,120 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYB5R4-associated genes across cancer lineages are PLEK, RHOH, and FPR2. Each is linked with CYB5R4 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYB5R4-to-partner and partner-to-CYB5R4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5R4 versus PLEK in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R4→partner) and Y-score (partner→CYB5R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLEK →	+1.130	+0.332	<.001	.001	3	7
HNSC	RHOH →	+0.888	+0.199	<.001	.006	2	8
LSCC	FPR2 →	+0.947	+0.200	<.001	<.001	3	7
UCEC	BCL2A1 →	+1.257	+0.232	<.001	.003	3	7
CCRCC	SLAMF8 →	+0.944	+0.280	<.001	.003	3	7
LSCC	KYNU →	+1.054	+0.208	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,120 associations by consensus.

CYB5R4 vs PLEK — OV

Explore this scatter interactively →