CYB5R4

Across TCGA cell cohorts, CYB5R4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,630 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CYB5R4-associated GO terms across cancer lineages are Detection of oxygen, 7-methylguanosine RNA capping, and 7-methylguanosine mRNA capping. Each is linked with CYB5R4 in more than 15 cancer types. Because this analysis shows association rather than direction, both CYB5R4-to-partner and partner-to-CYB5R4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of oxygen grouped by CYB5R4-low versus CYB5R4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R4→partner) and Y-score (partner→CYB5R4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Detection of oxygen →	+0.174	+0.903	.001	.004	3	16
OVARY	7-methylguanosine RNA capping →	+0.104	+0.839	.002	.004	3	13
OVARY	7-methylguanosine mRNA capping →	+0.104	+0.839	.002	.004	3	13
LIVER	Phosphatidylinositol dephosphorylation →	+0.068	+1.057	.009	.003	3	12
STOMACH	Phosphatidylinositol biosynthetic process →	+0.070	+0.968	<.001	.001	3	12
LIVER	Melanosome assembly →	+0.153	+1.184	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,630 associations by consensus.

Detection of oxygen by CYB5R4 expression — URINARY_TRACT

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