CYB5R2

Across TCGA patient cohorts, CYB5R2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYB5R2-associated proteins across cancer lineages are PPFIBP2, PPFIBP2_S387, and PPFIBP2_S512. Each is linked with CYB5R2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CYB5R2-to-partner and partner-to-CYB5R2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5R2 versus PPFIBP2 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R2→partner) and Y-score (partner→CYB5R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPFIBP2 →	+0.359	+0.579	<.001	<.001	3	7
LUAD	PPFIBP2_S387 →	+0.700	+0.514	<.001	<.001	3	6
BRCA	PPFIBP2_S512 →	+0.793	+0.916	<.001	<.001	3	4
UCEC	TPD52L1 →	+0.777	+0.769	<.001	.001	3	4
BRCA	EPB41L2_S386 →	+0.828	+1.248	<.001	<.001	3	4
LUAD	PPFIBP2_S329 →	+0.913	+0.384	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,385 associations by consensus.

CYB5R2 vs PPFIBP2 — LUAD

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