CYB5R2

Across TCGA cell cohorts, CYB5R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,729 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYB5R2-associated GO terms across cancer lineages are Rho protein signal transduction, Negative regulation of response to endoplasmic reticulum stress, and Vacuolar transport. Each is linked with CYB5R2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CYB5R2-to-partner and partner-to-CYB5R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rho protein signal transduction grouped by CYB5R2-low versus CYB5R2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R2→partner) and Y-score (partner→CYB5R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Rho protein signal transduction →	+0.117	+2.200	.001	<.001	3	9
BONE	Negative regulation of response to endoplasmic reticulum stress →	+0.120	+1.999	<.001	.003	3	8
LUNG_SCLC	Vacuolar transport →	+0.044	+1.366	<.001	<.001	3	8
BONE	Endosome to lysosome transport →	+0.060	+2.213	<.001	.002	3	8
BONE	Positive regulation of plasma membrane repair →	+0.244	+2.033	<.001	<.001	3	7
BONE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.562	+2.435	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,729 associations by consensus.

Rho protein signal transduction by CYB5R2 expression — PANCREAS

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