CYB5R2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CYB5R2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYB5R2-associated genes across cancer lineages are CCL16. Each is linked with CYB5R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5R2-to-partner and partner-to-CYB5R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL16 grouped by CYB5R2-low versus CYB5R2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R2→partner) and Y-score (partner→CYB5R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCL16 →+0.048+3.758<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CCL16 by CYB5R2 expression — LARGE_INTESTINE

Box plot of CCL16 in CYB5R2-low vs CYB5R2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration