CYB5R1

Across TCGA patient cohorts, CYB5R1 mutation is significantly associated with the RNA expression of many other genes, with 1,631 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB5R1-associated genes across cancer lineages are MTND5P35, RNU6-522P, and SNRPBP1. Each is linked with CYB5R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5R1-to-partner and partner-to-CYB5R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND5P35 grouped by CYB5R1-low versus CYB5R1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R1→partner) and Y-score (partner→CYB5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTND5P35 →	+0.033	+6.124	<.001	<.001	3	2
SKCM	RNU6-522P →	+0.234	+4.385	<.001	.008	3	2
UCEC	SNRPBP1 →	+0.223	+1.891	.001	.007	3	2
BLCA	RN7SKP3 →	+0.084	+5.289	<.001	.003	3	2
BLCA	RN7SL97P →	+0.096	+4.497	<.001	.009	3	2
BRCA	OR7E156P →	+0.509	+5.122	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,631 associations by consensus.

MTND5P35 by CYB5R1 expression — CESC

Explore this box plot interactively →