CYB5R1

Across TCGA cell cohorts, CYB5R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,933 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYB5R1-associated GO terms across cancer lineages are Membrane protein proteolysis, Lysosomal lumen acidification, and Endosome organization. Each is linked with CYB5R1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CYB5R1-to-partner and partner-to-CYB5R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane protein proteolysis grouped by CYB5R1-low versus CYB5R1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R1→partner) and Y-score (partner→CYB5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Membrane protein proteolysis →	+0.116	+0.692	.001	.002	3	13
CNS	Lysosomal lumen acidification →	+0.117	+0.619	<.001	.003	3	12
BLOOD_Lymphoma	Endosome organization →	+0.027	+0.570	.001	<.001	3	11
OESOPHAGUS	Vacuolar transport →	+0.070	+0.999	<.001	.007	3	10
BREAST	'de novo' IMP biosynthetic process →	-0.088	-0.649	<.001	<.001	3	10
BLOOD_Myeloma	Endoplasmic reticulum organization →	+0.089	+1.352	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

Membrane protein proteolysis by CYB5R1 expression — PANCREAS

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