CYB5D1

Across TCGA patient cohorts, CYB5D1 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CYB5D1-associated genes across cancer lineages are CCDC75P1, RNA5SP447, and RNU1-84P. Each is linked with CYB5D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5D1-to-partner and partner-to-CYB5D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC75P1 grouped by CYB5D1-low versus CYB5D1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5D1→partner) and Y-score (partner→CYB5D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CCDC75P1 →	+0.054	+4.973	<.001	.009	3	1
BLCA	RNA5SP447 →	+0.370	+5.329	<.001	.006	3	1
BLCA	RNU1-84P →	+0.286	+5.788	<.001	.003	3	1
BLCA	OR2U1P →	+0.086	+5.685	<.001	.003	3	1
BLCA	TRAJ43 →	+0.801	+5.588	<.001	.004	3	1
BLCA	TRAJ25 →	+0.618	+5.106	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

CCDC75P1 by CYB5D1 expression — BLCA

Explore this box plot interactively →