CYB5B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYB5B protein abundance is significantly associated with the RNA expression of many other genes, with 10,573 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CYB5B-associated genes across cancer lineages are STAG1, NUTF2, and COG4. Each is linked with CYB5B in more than 4 cancer types. Because this analysis shows association rather than direction, both CYB5B-to-partner and partner-to-CYB5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5B versus STAG1 in UCEC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5B→partner) and Y-score (partner→CYB5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSTAG1 →-0.475-0.627<.001<.00135
OVNUTF2 →+0.474+0.361<.001<.00134
OVCOG4 →+0.597+0.300<.001<.00134
OVRIOK1 →-0.416-0.258<.001.00134
UCECGNL3 →-0.588-0.474<.001<.00134
OVMELK →-1.000-0.269<.001.00534
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,573 associations by consensus.

CYB5B vs STAG1 — UCEC

Per-sample scatter of CYB5B vs STAG1 in UCEC (Pearson r = -0.28).

Explore this scatter interactively →

Exploration