CYB5B

Across TCGA patient cohorts, CYB5B mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB5B-associated genes across cancer lineages are Endothelial cells, mv Endothelial cells, and Basophils. Each is linked with CYB5B in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5B-to-partner and partner-to-CYB5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CYB5B-low versus CYB5B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5B→partner) and Y-score (partner→CYB5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.033	-2.764	.045	.003	3	1
UCEC	mv Endothelial cells →	-0.023	-2.947	.025	.036	3	1
UCEC	Basophils →	+0.247	+3.584	<.001	.002	3	1
UCEC	pDC →	+0.059	+2.329	.005	.020	3	1
UCEC	pro B-cells →	+0.096	+2.185	.041	.034	3	1
UCEC	Smooth muscle →	-0.133	-2.305	.015	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Endothelial cells by CYB5B expression — UCEC

Explore this box plot interactively →