CYB5B

Across TCGA cell cohorts, CYB5B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYB5B-associated GO terms across cancer lineages are DNA strand elongation, R-loop processing, and Positive thymic T cell selection. Each is linked with CYB5B in more than 9 cancer types. Because this analysis shows association rather than direction, both CYB5B-to-partner and partner-to-CYB5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by CYB5B-low versus CYB5B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5B→partner) and Y-score (partner→CYB5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA strand elongation →	+0.149	+1.155	<.001	<.001	3	10
OVARY	R-loop processing →	+0.090	+1.307	<.001	<.001	3	10
OVARY	Positive thymic T cell selection →	+1.003	+1.239	.003	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.186	+0.962	<.001	.002	3	10
BREAST	Basolateral protein secretion →	+0.169	+0.992	<.001	<.001	3	9
BLOOD_Lymphoma	Mitotic DNA replication →	+0.123	+0.859	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,108 associations by consensus.

DNA strand elongation by CYB5B expression — BLOOD_Lymphoma

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