CYB5A

Across TCGA patient cohorts, CYB5A mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB5A-associated genes across cancer lineages are RN7SL248P, RNA5SP226, and EIF2S2P7. Each is linked with CYB5A in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5A-to-partner and partner-to-CYB5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CYB5A-low versus CYB5A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5A→partner) and Y-score (partner→CYB5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.154	+4.722	<.001	.004	3	2
SKCM	RNA5SP226 →	+0.412	+5.159	<.001	.007	3	2
UCEC	EIF2S2P7 →	+0.101	+3.677	<.001	.006	3	1
UCEC	RN7SL840P →	+0.597	+3.454	<.001	.006	3	1
BLCA	RN7SKP28 →	+0.195	+5.588	.002	.004	3	1
BLCA	MIR640 →	+0.337	+5.251	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RN7SL248P by CYB5A expression — UCEC

Explore this box plot interactively →