CYB561D2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYB561D2 protein abundance is significantly associated with the RNA expression of many other genes, with 389 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYB561D2-associated genes across cancer lineages are HSCB, ORC4, and PAEP. Each is linked with CYB561D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB561D2-to-partner and partner-to-CYB561D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB561D2 versus HSCB in BRCA, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561D2→partner) and Y-score (partner→CYB561D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAHSCB →-1.292-0.864.004.00431
BRCAORC4 →+0.925+0.820.007.00131
BRCAPAEP →+0.932+0.865<.001.00431
BRCADBH →-0.560-0.800.009.00931
BRCAGALR3 →+0.426+0.862.007.00831
BRCASYN2 →-1.455-0.865<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 389 associations by consensus.

CYB561D2 vs HSCB — BRCA

Per-sample scatter of CYB561D2 vs HSCB in BRCA (Pearson r = -0.82).

Explore this scatter interactively →

Exploration