CYB561D2

Across TCGA patient cohorts, CYB561D2 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYB561D2-associated genes across cancer lineages are LSP1P3, OR4K3, and HBZP1. Each is linked with CYB561D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB561D2-to-partner and partner-to-CYB561D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSP1P3 grouped by CYB561D2-low versus CYB561D2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561D2→partner) and Y-score (partner→CYB561D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSP1P3 →	+0.515	+3.063	<.001	.008	3	1
UCEC	OR4K3 →	+0.079	+4.496	<.001	<.001	3	1
BLCA	HBZP1 →	+0.114	+7.640	<.001	.009	3	1
UCEC	RNA5SP405 →	+0.509	+4.260	<.001	.007	3	1
UCEC	RNU6-674P →	+0.682	+3.701	<.001	.001	3	1
UCEC	RNU6-194P →	+0.637	+3.797	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

LSP1P3 by CYB561D2 expression — UCEC

Explore this box plot interactively →