CYB561D2

Across TCGA cell cohorts, CYB561D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,519 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CYB561D2-associated GO terms across cancer lineages are Ascorbate homeostasis, GDP-mannose biosynthetic process, and GDP-mannose metabolic process. Each is linked with CYB561D2 in more than 15 cancer types. Because this analysis shows association rather than direction, both CYB561D2-to-partner and partner-to-CYB561D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ascorbate homeostasis grouped by CYB561D2-low versus CYB561D2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561D2→partner) and Y-score (partner→CYB561D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Ascorbate homeostasis →	+0.215	+1.302	<.001	<.001	3	16
URINARY_TRACT	GDP-mannose biosynthetic process →	+0.133	+1.151	.003	.006	3	12
UPPER_AERODIGESTIVE_TRACT	GDP-mannose metabolic process →	+0.106	+0.716	.005	.006	3	11
SOFT_TISSUE	Protein retention in ER lumen →	+0.119	+0.706	<.001	.002	3	11
BLOOD_Myeloma	Mitochondrial potassium ion transmembrane transport →	+0.165	+0.838	<.001	.001	3	10
SKIN	Positive regulation of store-operated calcium channel activity →	+0.154	+1.010	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,519 associations by consensus.

Ascorbate homeostasis by CYB561D2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →