CXorf58

Across TCGA pan-cancer cohorts, CXorf58 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CXorf58 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in acute myeloid leukemia (LAML), where higher CXorf58 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CXorf58 expression acts as an unfavorable survival marker.

LAML, HNSC, and UCEC are the cancer types where CXorf58 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LAML	DFS	Median	All	0.082	0.582	.004	12	view →
HNSC	DFS	Median	II,III,IV	0.156	0.612	.022	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CXorf58–LAML (DFS)

Open the LAML breakdown →