CXorf56

Across TCGA cell cohorts, CXorf56 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,565 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CXorf56-associated GO terms across cancer lineages are Negative regulation of protein ubiquitination, U2-type prespliceosome assembly, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with CXorf56 in more than 13 cancer types. Because this analysis shows association rather than direction, both CXorf56-to-partner and partner-to-CXorf56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein ubiquitination grouped by CXorf56-low versus CXorf56-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf56→partner) and Y-score (partner→CXorf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of protein ubiquitination →	+0.075	+0.678	.003	.003	2	14
UPPER_AERODIGESTIVE_TRACT	U2-type prespliceosome assembly →	+0.109	+0.891	.002	<.001	2	13
BLOOD_Lymphoma	Positive regulation of telomerase RNA localization to Cajal body →	+0.096	+1.053	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nucleus organization →	+0.065	+0.872	.001	<.001	3	11
SOFT_TISSUE	Regulation of protein modification by small protein conjugation or removal →	+0.046	+0.801	<.001	<.001	3	11
BREAST	Negative regulation of protein modification by small protein conjugation or removal →	+0.096	+0.935	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,565 associations by consensus.

Negative regulation of protein ubiquitination by CXorf56 expression — OVARY

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