Across TCGA pan-cancer cohorts, CXorf38 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CXorf38 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CXorf38 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CXorf38 expression acts as an unfavorable survival marker.

CCRCC, LSCC, and COAD are the cancer types where CXorf38 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.633	0.955	.001	32	view →
LSCC	OS	Median	II,III,IV	0.665	0.889	.009	8	view →
COAD	DFS	Quartile	III,IV	0.728	1.000	.044	6	view →
GBM	DFS	Tertile	All	0.608	0.835	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CXorf38 tumor-vs-normal RNA expression · all CXorf38 data types