Across TCGA pan-cancer cohorts, CXorf38 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CXorf38’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CXorf38 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CXorf38 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRC, HNSC, and COAD are the cancer types where CXorf38 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CXorf38 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.