Across TCGA patient cohorts, CXorf38 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXorf38-associated genes across cancer lineages are EGFR_pY1068, FASN, and FOXO3a. Each is linked with CXorf38 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXorf38-to-partner and partner-to-CXorf38 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf38→partner) and Y-score (partner→CXorf38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.260	-2.459	.010	.019	3	1
UCEC	FASN →	+0.390	+3.169	.014	.019	3	1
UCEC	FOXO3a →	-0.093	-1.970	.022	.030	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.355	+2.415	.039	.003	3	1
UCEC	JNK2 →	+0.194	+1.906	.015	.016	3	1
UCEC	MEK1 →	+0.334	+1.700	.023	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

CXorf38 survival (RNA) · tumor vs normal (RNA) · all CXorf38 data types