CXorf21

Across TCGA cell cohorts, CXorf21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,520 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CXorf21-associated GO terms across cancer lineages are Negative regulation of nucleocytoplasmic transport, Lipoprotein transport, and Lipoprotein localization. Each is linked with CXorf21 in more than 7 cancer types. Because this analysis shows association rather than direction, both CXorf21-to-partner and partner-to-CXorf21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nucleocytoplasmic transport grouped by CXorf21-low versus CXorf21-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf21→partner) and Y-score (partner→CXorf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of nucleocytoplasmic transport →	+0.079	+2.379	<.001	<.001	3	8
KIDNEY	Lipoprotein transport →	+0.135	+0.040	<.001	.004	3	7
KIDNEY	Lipoprotein localization →	+0.137	+0.047	<.001	<.001	3	7
BLOOD_Leukemia	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.098	+1.784	<.001	.001	3	7
CNS	Regulation of intracellular transport →	+0.040	+0.048	.001	.002	3	6
BLOOD_Lymphoma	Positive regulation of DNA recombination →	+0.066	+1.787	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

Negative regulation of nucleocytoplasmic transport by CXorf21 expression — BLOOD_Lymphoma

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