CXXC5

Across TCGA patient cohorts, CXXC5 protein abundance is significantly associated with the RNA expression of many other genes, with 17,249 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CXXC5-associated genes across cancer lineages are LINC01184, GIN1, and AGGF1. Each is linked with CXXC5 in more than 4 cancer types. Because this analysis shows association rather than direction, both CXXC5-to-partner and partner-to-CXXC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXXC5 versus LINC01184 in LUAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXXC5→partner) and Y-score (partner→CXXC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC01184 →	+0.488	+0.453	<.001	<.001	3	5
BRCA	GIN1 →	+0.453	+0.399	<.001	<.001	3	4
BRCA	AGGF1 →	+0.435	+0.574	<.001	<.001	3	4
CCRCC	RPL5P8 →	+0.759	+0.309	<.001	.001	3	4
LSCC	PERP →	-1.153	-0.735	<.001	<.001	3	4
GBM	RDH10 →	-1.189	-0.549	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,249 associations by consensus.

CXXC5 vs LINC01184 — LUAD

Explore this scatter interactively →