CXCR5

Across TCGA patient cohorts, CXCR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,542 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCR5-associated proteins across cancer lineages are LAT_S224, ARHGAP45, and WAS. Each is linked with CXCR5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXCR5-to-partner and partner-to-CXCR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCR5 versus LAT_S224 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCR5→partner) and Y-score (partner→CXCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LAT_S224 →	+1.037	+0.218	<.001	<.001	3	10
HNSC	ARHGAP45 →	+0.534	+0.222	<.001	<.001	3	9
BRCA	WAS →	+0.465	+0.117	<.001	<.001	3	9
COAD	ARHGAP15 →	+0.555	+0.068	<.001	.001	3	9
UCEC	ADA2 →	+0.605	+0.118	<.001	<.001	3	9
BRCA	DOCK2 →	+0.551	+0.121	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,542 associations by consensus.

CXCR5 vs LAT_S224 — LSCC

Explore this scatter interactively →