Across TCGA patient cohorts, CXCR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,336 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCR3-associated proteins across cancer lineages are WDFY4, DOCK10, and DOCK2. Each is linked with CXCR3 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXCR3-to-partner and partner-to-CXCR3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCR3→partner) and Y-score (partner→CXCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WDFY4 →	+0.622	+0.965	<.001	<.001	3	10
LSCC	DOCK10 →	+0.539	+0.932	<.001	<.001	3	10
GBM	DOCK2 →	+0.665	+0.615	<.001	<.001	3	10
HNSC	AIF1 →	+0.617	+0.951	<.001	<.001	3	10
HNSC	FYB1 →	+0.731	+1.000	<.001	<.001	3	10
OV	GBP4 →	+0.877	+1.041	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,336 associations by consensus.

Exploration

CXCR3 survival (RNA) · tumor vs normal (RNA) · all CXCR3 data types