Across TCGA cell cohorts, CXCR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,953 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CXCR3-associated GO terms across cancer lineages are Protein localization to cilium, Cellular response to tumor necrosis factor, and Regulation of cell proliferation in bone marrow. Each is linked with CXCR3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CXCR3-to-partner and partner-to-CXCR3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCR3→partner) and Y-score (partner→CXCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein localization to cilium →	-0.071	-0.085	<.001	.008	3	5
PANCREAS	Cellular response to tumor necrosis factor →	+0.066	+0.205	<.001	<.001	3	5
BLOOD_Myeloma	Regulation of cell proliferation in bone marrow →	-0.166	-1.667	.001	.005	3	5
PANCREAS	Intrinsic apoptotic signaling pathway →	+0.046	+0.197	.001	.003	3	4
PANCREAS	Cellular response to interleukin-1 →	+0.068	+0.186	.002	<.001	3	4
BLOOD_Myeloma	Fibroblast migration →	+0.168	+1.547	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,953 associations by consensus.

Exploration

CXCR3 survival (RNA) · tumor vs normal (RNA) · all CXCR3 data types